Orthotopic injection of an established syngeneic mouse oral cancer cell line (MOC1) induces a robust draining lymph node response.
Vikash KansalBrendan L C KinneyNicole C SchmittPublished in: bioRxiv : the preprint server for biology (2024)
When used orthotopically in the buccal mucosa, the MOC1 model induces a robust lymph node response and distinct pattern of immune cell infiltration, with peak immune infiltration by day 14.