Safety, Stability and Pharmacokinetic Properties of (super)Factor Va, a Novel Engineered Coagulation Factor V for Treatment of Severe Bleeding.
Andrew J GaleVikas BhatJean-Luc PellequerJohn H GriffinLaurent O MosnierAnnette Von DrygalskiPublished in: Pharmaceutical research (2016)
FVa has an appropriate safety and stability profile for further preclinical development as a prohemostatic against severe bleeding.