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Synergistic therapeutic combination with a CAF inhibitor enhances CAR-NK-mediated cytotoxicity via reduction of CAF-released IL-6.

Young Eun LeeGa-Yeon GoEun-Young KohHan-Na YoonMinkoo SeoSeung-Mo HongJi Hye JeongJin-Chul KimDuck ChoTae Sung KimSong Cheol KimEunsung JunMihue Jang
Published in: Journal for immunotherapy of cancer (2023)
-CAF-containing pancreatic cancer allows improvements in the therapy of pancreatic ductal adenocarcinoma.
Keyphrases
  • nk cells
  • bone marrow
  • mesenchymal stem cells