Human Papillomavirus Vaccination and Premature Ovarian Failure: A Disproportionality Analysis Using the Vaccine Adverse Event Reporting System.

Collins TatangTeigna Arredondo BisonóAurore BergamascoFrancesco SalvoSue Ann Costa ClemensYola Moride

Published in: Drugs - real world outcomes (2021)

Our study suggests the presence of a potential safety signal of POF associated with HPV vaccination, which may only be partly attributed to notoriety bias. Due to the well-known limitations of spontaneous reporting data, further investigations are warranted.

Keyphrases

adverse drug
electronic health record
high grade
emergency department
big data
human health
data analysis
cervical cancer screening