Effect of BTN162b2 and CoronaVac boosters on humoral and cellular immunity of individuals previously fully vaccinated with CoronaVac against SARS-CoV-2: A longitudinal study.

Zeynep Ece KuloğluRojbin ElGülen EskenYeşim TokZeynep Gülçe TalayTayfun BarlasMert Ahmet KuskucuOzgur AlbayrakÖzlem DoğanSerap Şimşek YavuzKenan MidilliÖnder ErgönülFüsun Can

Published in: Allergy (2022)

The neutralizing antibody levels after 3 months of the BNT booster were higher than the antibody levels after CV in fully vaccinated individuals. On the contrary, ratio of the effector T cells increased along with greater IFN-γ activation after BNT booster. By considering the waning immunity, we suggest a new booster dose with BNT for the countries that already had two doses of primary CV regimens.

Keyphrases

sars cov
immune response
dendritic cells
respiratory syndrome coronavirus
regulatory t cells
type iii