Genetic variations in the human immune system influence susceptibility to tegumentary leishmaniasis: a systematic review and meta-analysis.

Daniele Stéfanie Sara Lopes Lera-NonoseLarissa Ferreira De OliveiraAline BrustolinThais Silva SantosJully OyamaÁquila Carolina Fernandes Herculano Ramos-MilaréMariana De Souza Terron-MonichIzabel Galhardo DemarchiQuirino Alves De Lima NetoJorge Juarez Vieira TeixeiraMaria Valdrinez Campana Lonardoni

Published in: Expert review of clinical immunology (2021)

IL-1β_rs16944, TNF-α_rs1800629, MIF_rs755622, and INF-γ_rs2430561 polymorphisms were speculated as risk factor for TL, corroborating that IL-1β, TNF-α, INF-γ, and MIF are involved in the TL pathogenesis.

Keyphrases

rheumatoid arthritis
endothelial cells
genome wide
copy number