Cumulative incidence and risk factors for the development of hepatocellular carcinoma in patients with chronic hepatitis B who achieved sustained disappearance of viremia by nucleos(t)ide analog treatment.

Yusuke AndoMasatoshi IshigamiYoji IshizuTeiji KuzuyaTakashi HondaKazuhiko HayashiTetsuya IshikawaIsao NakanoYoshiki HirookaHidemi Goto

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2017)

Our findings indicate the importance of continuous HCC surveillance especially in patients with advanced age, cirrhosis, and/or higher serum levels of HBcrAg, even if they achieve HBV-DNA disappearance.

Keyphrases

hepatitis b virus
public health
circulating tumor
cell free
liver failure
liver fibrosis
replacement therapy
nucleic acid
smoking cessation