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Innate lymphoid cells in isocyanate-induced asthma: role of microRNA-155.

Evy E BlommeSharen ProvoostErica BazzanHannelore P Van EeckhoutteMirjam P RoffelLore PollarisAnnelies BontinckMatteo BonatoLouise VandenbrouckeFien VerhammeGuy F JoosManuel G CosioJeroen A J VanoirbeekGuy G O BrusselleMarina SaettaTania Maes
Published in: The European respiratory journal (2020)
TDI exposure is associated with increased numbers of ILCs. The proinflammatory microRNA-155 is crucial in a murine model of TDI asthma, suggesting its involvement in the pathogenesis of occupational asthma due to low molecular weight agents.
Keyphrases
  • chronic obstructive pulmonary disease
  • lung function
  • allergic rhinitis
  • induced apoptosis
  • cell cycle arrest
  • cystic fibrosis
  • air pollution
  • diabetic rats
  • drug induced
  • endothelial cells