A Family and a Genome-Wide Polygenic Risk Score Are Independently Associated With Stroke in a Population-Based Study.
Michelle HämmerleLukas ForerSebastian SchönherrAnnette PetersHarald GrallertFlorian KronenbergChristian GiegerClaudia LaminaPublished in: Stroke (2022)
Our study shows that a family risk score and PGS capture different information concerning individual stroke risk. Combining the risk measures FamRS and PGS increases predictive power, as demonstrated in a population-based study.