Punicalagin, a Pomegranate-Derived Ellagitannin, Suppresses Obesity and Obesity-Induced Inflammatory Responses Via the Nrf2/Keap1 Signaling Pathway.

Bobin KangChae Young KimJisu HwangKyungae JoSingeun KimHyung Joo SuhHyeon-Son Choi

Published in: Molecular nutrition & food research (2019)

PCG ameliorates obesity and obesity-induced inflammatory responses via activation of Nrf2/Keap1 signaling, suggesting that PCG has potential as an oral agent to control obesity-mediated diseases.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
signaling pathway
oxidative stress
adipose tissue
high glucose
skeletal muscle
physical activity
mouse model
climate change
small molecule
protein protein