Patient-reported outcomes on sleep quality and circadian rhythm during treatment with intravenous ketamine for treatment-resistant depression.

Raymond YanTyler MarshallAtul KhullarTravis NagleJake KnowlesMai MalkinBrittany ChubbsJennifer Swainson

Published in: Therapeutic advances in psychopharmacology (2024)

IV ketamine may improve sleep quality and advance circadian rhythm in individuals with TRD. Effects may differ in individuals with mixed features of depression as compared to those without. Since this was a small uncontrolled study, future research is warranted.

Keyphrases

sleep quality
patient reported outcomes
depressive symptoms
physical activity
atrial fibrillation
pain management
heart rate
high dose
current status
chronic pain