Login / Signup

Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer.

Henriette H NerildAndreas BrøndenAbdullah E HaddouchiAnne-Marie EllegaardBolette HartmannJens F RehfeldJens J HolstDavid P SonneTina VilsbøllFilip K Krag Knop
Published in: Diabetes, obesity & metabolism (2023)
we were not able to detect a GLP-1-mediated glucose-lowering effect of sevelamer in individuals with type 2 diabetes. Nevertheless, the sevelamer-induced improvement of beta-cell sensitivity to glucose was shown to be GLP-1-dependent.
Keyphrases
  • blood glucose
  • single cell
  • cell therapy
  • stem cells
  • diabetic rats
  • blood pressure
  • metabolic syndrome
  • adipose tissue
  • weight loss
  • insulin resistance