Advances in Chemistry and Bioactivity of Magnoflorine and Magnoflorine-Containing Extracts.
Estera OkonWirginia Kukuła-KochAgata JarzabMarta HalasaAndrzej StepulakAnna WawruszakPublished in: International journal of molecular sciences (2020)
The review collects together some recent information on the identity and pharmacological properties of magnoflorine, a quaternary aporphine alkaloid, that is widely distributed within the representatives of several botanical families like Berberidaceae, Magnoliaceae, Papaveraceae, or Menispermaceae. Several findings published in the scientific publications mention its application in the treatment of a wide spectrum of diseases including inflammatory ones, allergies, hypertension, osteoporosis, bacterial, viral and fungal infections, and some civilization diseases like cancer, obesity, diabetes, dementia, or depression. The pharmacokinetics and perspectives on its introduction to therapeutic strategies will also be discussed.
Keyphrases
- type diabetes
- blood pressure
- papillary thyroid
- metabolic syndrome
- insulin resistance
- cardiovascular disease
- mild cognitive impairment
- weight loss
- postmenopausal women
- depressive symptoms
- sars cov
- bone mineral density
- oxidative stress
- glycemic control
- squamous cell
- weight gain
- healthcare
- cognitive impairment
- systematic review
- sleep quality
- skeletal muscle
- adipose tissue
- body composition
- body mass index
- squamous cell carcinoma
- young adults