Cross-platform comparison of immune signatures in immunotherapy-treated patients with advanced melanoma using a rank-based scoring approach.

Yizhe MaoTuba N GideNurudeen A AdegokeCamelia QuekNigel MaherAlison PotterEllis PatrickRobyn P M SawJohn F ThompsonAndrew J SpillaneKerwin F ShannonMatteo S CarlinoSerigne N LoAlexander M MenziesInês Pires da SilvaGeorgina V LongRichard A ScolyerJames S Wilmott

Published in: Journal of translational medicine (2023)

Overall, the outcome of this study confirms that singscore based on NanoString data is a feasible approach to produce reliable signature scores for determining patients' immune profiles and the potential clinical utility in biomarker implementation, as well as to conduct cross-platform comparisons, such as WTS.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
healthcare
primary care
peritoneal dialysis
prognostic factors
gene expression
dna methylation
climate change