Flow Cytometry-Based Assay to Detect Alpha Galactosidase Enzymatic Activity at the Cellular Level.
Nóra FeketeLuca Kamilla LiGergely Tibor KozmaGyörgy FeketeÉva PallingerÁrpád Ferenc KovácsPublished in: Cells (2024)
A flow cytometry-based assay was developed for the quantitative detection of AGAL activity at the single-cell level, which may contribute to the diagnosis of Fabry patients.
Keyphrases
- flow cytometry
- high throughput
- single cell
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- high resolution
- prognostic factors
- nitric oxide
- patient reported outcomes
- heart failure
- loop mediated isothermal amplification
- mass spectrometry
- hypertrophic cardiomyopathy
- label free
- left ventricular