Malvidin From Malva sylvestris L. Ameliorates Allergic Responses in Ovalbumin-Induced Allergic Rhinitis Mouse Model via the STAT6/GATA3 Pathway.

Luo YiruiLi TaoLiu RuowuZhou JiaoZhou JingXu XiaodongYan YanClaus BachertDu JintaoLuo Ba

Published in: American journal of rhinology & allergy (2024)

Malvidin significantly improved allergic symptoms in an OVA-induced AR mouse model by modulating Th1/Th2 immune responses and suppressing the STAT6/GATA3 pathway, indicating its potential as a naturally sourced agent for AR management.

Keyphrases

allergic rhinitis
mouse model
immune response
high glucose
diabetic rats
transcription factor
cell proliferation
signaling pathway
drug induced
oxidative stress
physical activity
inflammatory response