Mid-Life Hemostasis Measures, 20-Year Cognitive Decline and Incident Dementia.
Aozhou WuA Richey SharrettAaron R FolsomAlvaro AlonsoKeenan A WalkerRebecca F GottesmanAlden L GrossAndreea M RawlingsAndrea Lauren Christman SchneiderJosef CoreshPublished in: Neurology (2023)
Overall, our study found consistent trend-associations of aPTT and factor VIII measured in mid-life with cognitive decline and incident dementia over 20 years, likely driven by vascular pathologies.