The effect of oral bisphosphonate therapy on vertebral morphometry and fractures in patients with Duchenne muscular dystrophy and glucocorticoid-induced osteoporosis.
Nat NasomyontCuixia TianLindsey HornungJane KhouryPaul M HochwaltJoshua Cole TildenBrenda L WongMeilan M RutterPublished in: Muscle & nerve (2021)
We observed stable prevalence of vertebral fractures and no change in severity by Genant grade in most vertebrae for up to 5 years of treatment. Oral BP may mitigate development or progression of vertebral fractures and be beneficial for secondary prevention of glucocorticoid-induced osteoporosis in this population.