Role of the Insulin-like Growth Factor (IGF) Axis in Diseases.

Published in: International journal of molecular sciences (2023)

The insulin-like growth factor axis is a multifaceted, complex system that comprises two ligands, IGF-I and IGF-II, receptors (IGF-1R, IGF-IIR, insulin receptor isoforms IR-A and B, and hybrid receptors) six high affinity IGF-binding proteins (IGFBPs 1-6), and IGFBP proteases [...].

Keyphrases

growth hormone
binding protein
pi k akt
signaling pathway
cell proliferation
weight loss
glycemic control