Plasma Surfactant Protein-D, Matrix Metalloproteinase-7, and Osteopontin Index Distinguishes Idiopathic Pulmonary Fibrosis from Other Idiopathic Interstitial Pneumonias.

Eric S WhiteMeng XiaSusan MurrayRachel DyalCandace M FlahertyKevin R FlahertyBethany B MooreLing ChengTracy J DoyleJulian VillalbaPaul F DellaripaIvan O RosasJonathan D KurtisFernando J Martinez

Published in: American journal of respiratory and critical care medicine (2017)

A biomarker index of SP-D, MMP-7, and osteopontin enhanced diagnostic accuracy in patients with IPF compared with those with non-IPF ILD. Our data suggest that this biomarker index may improve diagnostic confidence in IPF.

Keyphrases

idiopathic pulmonary fibrosis
interstitial lung disease
electronic health record
rheumatoid arthritis
machine learning
systemic sclerosis
cell migration