Relationship between thiol-disulphide homeostasis and visual evoked potentials in patients with multiple sclerosis.
Gönül VuralŞadiye GümüşyaylaOrhan DenizSalim NeşelioğluÖzcan ErelPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2018)
As the balance of the plasma dominated by antioxidants moves towards the oxidant side, in other words as a higher rate of thiol is oxidised from the thiol pool, P100 latency is extended. N-acetylcysteine and alpha lipoic acid as well as thiol supplements can improve the thiol-disulphide balance, reinforce antioxidant defence and it can help in slowing down the demyelinating damage.
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