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Abnormal (Hydroxy)proline Deuterium Content Redefines Hydrogen Chemical Mass.

Hassan GharibiAlexey L ChernobrovkinGunilla ErikssonAmir Ata SaeiZena TimmonsAndrew C KitchenerDaniela C KalthoffKerstin LidénAlexander A MakarovRoman A Zubarev
Published in: Journal of the American Chemical Society (2022)
Analyzing the δ 2 H values in individual amino acids of proteins extracted from vertebrates, we unexpectedly found in some samples, notably bone collagen from seals, more than twice as much deuterium in proline and hydroxyproline residues than in seawater. This corresponds to at least 4 times higher δ 2 H than in any previously reported biogenic sample. We ruled out diet as a plausible mechanism for such anomalous enrichment. This finding puts into question the old adage that "you are what you eat".
Keyphrases
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