Photoantibacterial Poly(vinyl)chloride Films Applying Curcumin Derivatives as Bio-Based Plasticizers and Photosensitizers.
Fábio M S RodriguesIúri TavaresRafael T ArosoLucas D DiasCarolina V DomingosClara Maria Gonçalves De FariaGiusi PiccirilloTeresa M R MariaRui M B CarrilhoVanderlei Salvador BagnatoMário J F CalveteMariette M PereiraPublished in: Molecules (Basel, Switzerland) (2023)
Herein we describe the design of natural curcumin ester and ether derivatives and their application as potential bioplasticizers, to prepare photosensitive phthalate-free PVC-based materials. The preparation of PVC-based films incorporating several loadings of newly synthesized curcumin derivatives along with their standard solid-state characterization is also described. Remarkably, the plasticizing effect of the curcumin derivatives in the PVC material was found to be similar to that observed in previous PVC-phthalate materials. Finally, studies applying these new materials in the photoinactivation of S. aureus planktonic cultures revealed a strong structure/activity correlation, with the photosensitive materials reaching up to 6 log CFU reduction at low irradiation intensities.