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Histopathology of anastomotic stenosis after total anomalous pulmonary vein connection.

Naoki MasakiMasahiro MizumotoOsamu AdachiSadahiro Sai
Published in: Interactive cardiovascular and thoracic surgery (2021)
We report a case of a 10-month-old girl who was diagnosed with pulmonary vein stenosis after total anomalous pulmonary vein connection repair and underwent release of an anastomotic stenosis. Histopathological examinations of the resected anastomotic tissue revealed intimal hyperplasia at the anastomotic site. Predominant lesion cells were identified as myofibroblasts and had the characteristics of fibroblasts and synthetic smooth muscle cells. These cells could be a useful target for preventing anastomotic stenosis after total anomalous pulmonary vein connection repair.
Keyphrases
  • rectal cancer
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • oxidative stress
  • signaling pathway
  • extracellular matrix