Single-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient.

Hye Won LeeWoosung ChungHae-Ock LeeDa Eun JeongAreum JoJoung Eun LimJeong Hee HongDo-Hyun NamByong Chang JeongSe Hoon ParkKyeung-Min JooWoong-Yang Park

Published in: Genome medicine (2020)

We presented a single case report demonstrating the power of scRNA-seq for visualizing the tumor microenvironment and identifying molecular and cellular therapeutic targets in a treatment-refractory cancer patient.

Keyphrases

case report
single cell
rna seq
high throughput
genome wide
dna methylation
replacement therapy
single molecule
lymph node metastasis
smoking cessation