Maternal rheumatoid arthritis and risk of autism in the offspring.
Weiyao YinMattias NorrbäckStephen Z LevineNatalia RiveraJoseph D BuxbaumHailin ZhuBenjamin YipAbraham ReichenbergJohan AsklingSven SandinPublished in: Psychological medicine (2023)
In Sweden, maternal RA before delivery was associated with an increased risk of offspring ASD. The comparable association between maternal arthralgia and ASD risk suggests other pathways of risk than autoimmunity/inflammation, acting jointly or independently of RA.
Keyphrases
- rheumatoid arthritis
- autism spectrum disorder
- birth weight
- pregnancy outcomes
- intellectual disability
- disease activity
- high fat diet
- oxidative stress
- attention deficit hyperactivity disorder
- ankylosing spondylitis
- metabolic syndrome
- body mass index
- adipose tissue
- systemic lupus erythematosus
- systemic sclerosis
- pregnant women
- skeletal muscle
- weight loss
- preterm birth
- idiopathic pulmonary fibrosis