5α,6α-Epoxyphytosterols and 5α,6α-Epoxycholesterol Increase Nitrosative Stress and Inflammatory Cytokine Production in Rats on Low-Cholesterol Diet.

Tomasz Wielkoszyński Jolanta Zalejska Fiolka Joanna Katarzyna Strzelczyk Aleksander Jerzy Owczarek Armand CholewkaKatarzyna KokoszczykAgata Stanek

Published in: Oxidative medicine and cellular longevity (2020)

The results indicate that oxidized plant sterols have a similar toxicity profile to that of oxycholesterols, including nitrosative stress induction, proinflammatory effect, and impaired lipid metabolism.

Keyphrases

low density lipoprotein
oxidative stress
physical activity
stress induced
weight loss