Acute kidney injury associated with febuxostat and allopurinol: a post-marketing study.

Amayelle ReyBenjamin BatteuxSolène M LavilleJustine MarienneKamel MasmoudiValérie Gras-ChampelSophie Liabeuf

Published in: Arthritis research & therapy (2019)

Acute renal failure was reported respectively 5.7 and 3.3 times more frequently for febuxostat and for allopurinol than for other drugs. Due to the potential consequences of ARF, physicians should take account of this disproportionality signal when prescribing the ULTs febuxostat and allopurinol.

Keyphrases

acute kidney injury
primary care
liver failure
drug induced
cardiac surgery
respiratory failure
emergency department
risk assessment
hepatitis b virus
human health
adverse drug
electronic health record
mechanical ventilation