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Receptive Language Abilities for Females Exposed to Early Life Adversity: Modification by Epigenetic Age Acceleration at Midlife in a 30-year Prospective Cohort Study.

John M FeltKarra D HarringtonNilam RamKieran J O'DonnellMartin John SliwinskiLizbeth BensonZhenyu ZhangMichael J MeaneyFrank W PutnamJennie G NollChad E Shenk
Published in: The journals of gerontology. Series B, Psychological sciences and social sciences (2022)
ELA is associated with significant differences in development of receptive language abilities with the most pronounced differences observed for females with accelerated epigenetic ages at mid-life. These findings suggest that epigenetic age acceleration could serve as an indicator of differences in cognitive aging and portend to later adulthood cognitive functioning.
Keyphrases
  • early life
  • dna methylation
  • gene expression
  • autism spectrum disorder