The duration of antibiotic therapy for fracture related infection does not affect recurrence but leads to increased adverse effects: a comparison among 6, 12 and 24 weeks of treatment.
Túlio Vinícius de Oliveira CamposMarco Antonio Percope de AndradeMarcelo PerucciFelipe Maciel SantosRafael Luiz de Pinho Teixeira MourãoRobinson Esteves Santos PiresSimony da Silva GonçalvesEdna Marileia Meireles LeitePublished in: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie (2024)
Antibiotic therapy longer than 6 weeks did not reduce the recurrence of FRI after one year of follow-up. Additionally, antibiotic treatment for 24 weeks increases adverse events such as skin reactions and acute renal failure.