MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression.

Yaojie FuBryan MackowiakDechun FengHongkun LuYukun GuanTaylor LehnerHongna PanXin Wei WangYong HeBin Gao

Published in: Gut (2023)

The miR-223 plays a critical role in modulating hypoxia-induced tumour immunosuppression and angiogenesis, which may serve as a novel therapeutic target for HCC.

Keyphrases

endothelial cells
vascular endothelial growth factor
cell proliferation
long non coding rna
wound healing
long noncoding rna
signaling pathway