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Infiltration of Mature KLRG1 Expressing Cytotoxic T Cells in Oral Lichen Planus.

Dulce Soler-FerranFabiola LouisSook-Bin WooSteven A Greenberg
Published in: Head and neck pathology (2022)
OLP oral mucosa T cell infiltration includes KLRG1 + highly differentiated cytotoxic T cells, suggesting continued antigen exposure driving T cells to a highly differentiated phenotype. The known phenotype of these cells, together with microarray detected increases in cytotoxic molecules, suggests that highly differentiated cytotoxic T cells contribute to oral mucosa injury in OLP.
Keyphrases
  • cell cycle arrest