Whole genome-based antimicrobial resistance and virulence profiling of Staphylococcus aureus isolates from chronic leg ulcer patients in Kilimanjaro, Tanzania.
Omar Said OmarLameck Pashet SengeruanLivin E KanjeMarco van ZwetselaarDavis John KuchakaMariana J ShayoHappiness KumburuTolbert SondaJere MshanaSamwel ChuguluPublished in: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases (2024)
Presence of mecA positive S. aureus isolates which are also phenotypically susceptible to cefoxitin implies the possibility of classifying MRSA as MSSA. This may result in the possible emergence of highly cefoxitin - resistant strains in health care and community settings when subsequently exposed to beta-lactam agents. Therefore, combination of whole genome sequencing and conventional methods is important in assessing bacterial resistance and virulence to improve management of patients.
Keyphrases
- antimicrobial resistance
- staphylococcus aureus
- healthcare
- escherichia coli
- biofilm formation
- end stage renal disease
- methicillin resistant staphylococcus aureus
- pseudomonas aeruginosa
- newly diagnosed
- chronic kidney disease
- ejection fraction
- mental health
- peritoneal dialysis
- social media
- patient reported outcomes
- patient reported
- candida albicans