The papillomavirus E5 gene does not affect EGFR transcription and overall survival in cervical cancer.

Diogo Lisbôa BastoCláudia Bessa Pereira ChavesShayany Pinto FelixSérgio Menezes Amaro-FilhoValdimara Corrêa VieiraLuís Felipe Leite MartinsNeile Alves de CarvalhoLiz Maria AlmeidaMiguel Angelo Martins Moreira

Published in: Journal of medical virology (2019)

The likely presence of E5 transcripts was neither associated to a higher activity of the EGFR-VEGFA pathway nor to the overall survival of patients with HPV16+ squamous cell carcinoma in stages ≥ IB2.

Keyphrases

small cell lung cancer
squamous cell carcinoma
epidermal growth factor receptor
tyrosine kinase
free survival
high grade
transcription factor
copy number
genome wide
gene expression
lymph node metastasis
radiation therapy