Proportion of toxin and non-toxin virulence factors of Staphylococcus aureus isolates from diabetic foot infection: a systematic review and meta-analysis.
Samaneh Shahrokh EsfahaniAliye TabatabaeeMaryam YazdiMansour SiavashPublished in: BMC microbiology (2024)
The results of the present study showed that among the toxin virulence factors, hemolysins (hld, hlg, hla, hlgv) and luk-ED and among the non-toxin virulence factors, icaA and icaD have the greatest proportion in S. aureus isolates from DFIs. These prevalent genes may have the potential to evaluate as virulence factors involved in DFI pathogenesis. Finding these probable virulence factor genes can help control diabetic foot infection more effectively via anti-virulence therapy or preparation of multi-epitope vaccines.
Keyphrases
- escherichia coli
- staphylococcus aureus
- biofilm formation
- pseudomonas aeruginosa
- antimicrobial resistance
- emergency department
- genome wide
- candida albicans
- cystic fibrosis
- methicillin resistant staphylococcus aureus
- risk assessment
- bone marrow
- high resolution
- tandem mass spectrometry
- smoking cessation
- molecularly imprinted
- replacement therapy