Structural and functional damage to neuronal nuclei caused by extracellular tau oligomers.
Xuehan SunGuillermo EastmanYu ShiSubhi SaibabaAna K OliveiraJohn R LukensAndrés NorambuenaJames W MandellGeorge S BloomPublished in: bioRxiv : the preprint server for biology (2023)
, and by extension, impair nucleocytoplasmic transport and induce pathogenic gene expression changes.