Enhanced junctional epithelial permeability in TRPV4-deficient mice.
Tomoko KitsukiReiko U YoshimotoReona AijimaJunko HatakeyamaAi-Lin CaoJing-Qi ZhangYasuyoshi OhsakiYoshihide MoriMizuho A KidoPublished in: Journal of periodontal research (2019)
The present findings identify a crucial role for TRPV4 in the formation of adherens junctions in the junctional epithelium, which could regulate its permeability. TRPV4 may be a candidate pharmacological target to combat periodontal diseases.