Prognosis difference between HER2-low and HER2-zero breast cancer patients: a systematic review and meta-analysis.
Chengxin LiQianqian YuanTong DengGaoran XuJinxuan HouLewei ZhengGao-Song WuPublished in: Breast cancer (Tokyo, Japan) (2023)
HER2-low BC patients have longer OS and DFS compared to HER2-zero BC patients, and its prognostic value is consistent among different HR status patients. Whether HER2-low breast cancer is an independent subtype of breast cancer is still a subject of ongoing research, and more studies are needed to fully understand the molecular and clinical features of this subtype.