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A web application for the design of multi-arm clinical trials.

Michael John GraylingJames Ms Wason
Published in: BMC cancer (2020)
The application provides the core information required by statisticians and clinicians to review the operating characteristics of a chosen multi-arm clinical trial design. The range of designs supported by the application is broader than other currently available software solutions. Its primary limitation, particularly from a regulatory agency point of view, is its lack of validation. However, we present an approach to efficiently confirming its results via simulation.
Keyphrases
  • clinical trial
  • phase ii
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  • open label
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