A Molecular Study on Hepatitis E Virus (HEV) in Pigs in Bulgaria.
Andrea PalombieriIlia TsachevVittorio SarchesePaola FruciFederica Di ProfioRoman PepovichMagdalena BaymakovaFulvio MarsilioVito MartellaBarbara Di MartinoPublished in: Veterinary sciences (2021)
Information on hepatitis E virus (HEV) strains circulating in animal reservoirs in Bulgaria is currently lacking. Herein, by screening HEV seropositive sera obtained from Bulgarian swine and wild boars, viral RNA was detected at high prevalence rate (28.2%) in industrial pigs. Sequence analysis of the partial polymerase (RdRp) region revealed the highest genetic correlation with HEVs of genotype (Gt) 3 identified in French and Dutch patients. For three such strains, a 700-bp fragment of the open reading frame 2 gene was generated. On phylogenetic analysis, the Bulgarian strains clustered tightly (93.8-98.3% nt) with human and animal HEVs classified within the Gt3 subtype c.
Keyphrases
- escherichia coli
- end stage renal disease
- endothelial cells
- ejection fraction
- genome wide
- chronic kidney disease
- risk factors
- sars cov
- minimally invasive
- prognostic factors
- peritoneal dialysis
- healthcare
- gene expression
- health information
- dna methylation
- patient reported outcomes
- risk assessment
- transcription factor
- amino acid