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Ectopic parathyroid hormone as a rare aetiology of hypercalcemia with rhabdomyosarcoma: a new treatment strategy with zoledronic acid and Denosumab.

Fatih KilciUğur DemirsoyJeremy Huw JonesOzgur CakirFiliz Mine Çizmecioğlu-Jones
Published in: Journal of pediatric endocrinology & metabolism : JPEM (2022)
We report a patient with rhabdomyosarcoma accompanied by HCM, secondary to ectopic PTH, in whom the HCM was successfully managed with ZA and Denosumab. We believe that ZA should be the bisphosphonate of choice in pediatric HCM with rhabdomyosarcoma, while Denosumab may be another option in ZA-refractory cases.
Keyphrases
  • bone mineral density
  • hypertrophic cardiomyopathy
  • giant cell
  • postmenopausal women
  • left ventricular
  • body composition
  • case report
  • combination therapy
  • atrial fibrillation
  • childhood cancer