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Temporal Characterization and Visualization of Revolving Therapy-Events in Lung Cancer Patients.

Jonas HügelDonata A SchäferJan J SchneiderJiazi TianHossein EstiriRaphael KochTobias R OverbeckUlrich Sax
Published in: Studies in health technology and informatics (2024)
This paper presents a comprehensive workflow for integrating revolving events into the transitive sequential pattern mining (tSPM+) algorithm and Machine Learning for Health Outcomes (MLHO) framework, emphasizing best practices and pitfalls in its application. We emphasize feature engineering and visualization techniques, demonstrating their efficacy in capturing temporal relationships. Applied to an EGFR lung cancer cohort, our approach showcases reliable temporal insights even in a small dataset. This work highlights the importance of temporal nuances in healthcare data analysis, paving the way for improved disease understanding and patient care.
Keyphrases
  • machine learning
  • healthcare
  • data analysis
  • deep learning
  • small cell lung cancer
  • primary care
  • stem cells
  • big data
  • electronic health record
  • bone marrow
  • mesenchymal stem cells
  • cell therapy
  • replacement therapy