H3 G34-mutant high-grade gliomas: integrated clinical, imaging and pathological characterisation of a single-centre case series.

José Pedro LavradorZita ReiszNaomi SibtainKapil RajwaniAsfand Baig MirzaFrancesco VerganiRichard GullanRanjeev BhangooKeyoumars AshkanCristina BleilBassel ZebianBarnaby ClarkRoss LaxtonAndrew KingIstvan BodiSafa Al-Saraj

Published in: Acta neurochirurgica (2023)

H3 G34R-mutant hemispheric glioma is a distinct entity with characteristic imaging and pathological features. Genomic landscaping of individual tumours can offer an opportunity to adapt individual therapies and improve patient management.

Keyphrases

high grade
high resolution
low grade
wild type
case report
gene expression
copy number
mass spectrometry
fluorescence imaging