Adenosine A2A receptors facilitate synaptic NMDA currents in CA1 pyramidal neurons.
Francisco M MouroDiogo M RomboRaquel B DiasJoaquim A RibeiroAna M SebastiãoPublished in: British journal of pharmacology (2018)
These results show that A2A receptors exert a positive postsynaptic modulatory effect over synaptic, but not extrasynaptic, NMDA receptors in CA1 neurons and, therefore, under non-pathological conditions may contribute to shift the dual role of NMDA receptors towards enhancement of synaptic plasticity.
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