Wnt3a promotes odonto/osteogenic differentiation in vitro and tertiary dentin formation in a rat model.

Waleerat SukarawanP RattanawarawipaKamonwan YaemkleebbuaN NowwaroteP PavasantC Nakalekha LimjeerajarusThanaphum Osathanon

Published in: International endodontic journal (2023)

Wnt3a suppressed proliferation, increased osteogenic differentiation of SHEDs and promotes tertiary dentine formation. Wnt3a could be utilised as biological molecule for vital pulp therapy.

Keyphrases

cell proliferation
stem cells
mesenchymal stem cells
bone marrow
signaling pathway
cell therapy