Clonal haematopoiesis of indeterminate potential and atrial fibrillation: an east Asian cohort study.
Hyo-Jeong AhnHong Yul AnGangpyo RyuJiwoo LimChoonghyun SunHan SongSu-Yeon ChoiHeesun LeeTaylor MaurerDaniel NachunSoonil KwonSo-Ryoung LeeGregory Yoke Hong LipSeil OhSiddhartha JaiswalYoungil KohEue-Keun ChoiPublished in: European heart journal (2024)
CHIP mutations, primarily DNMT3A or TET2, are more prevalent in patients with AF than non-AF subjects whilst their presence is associated with a more progressive nature of AF and unfavourable clinical outcomes.
Keyphrases
- atrial fibrillation
- oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- direct oral anticoagulants
- heart failure
- dna methylation
- multiple sclerosis
- percutaneous coronary intervention
- high throughput
- circulating tumor cells
- gene expression
- coronary artery disease
- human health
- venous thromboembolism
- left ventricular