MID1-PP2A complex functions as new insights in human lung adenocarcinoma.

Lin ZhangJunyao LiXuejiao LvTingting GuoWei LiJie Zhang

Published in: Journal of cancer research and clinical oncology (2018)

We demonstrated that the MID1-PP2A complex plays an important role in lung adenocarcinoma, influencing cell cycle progression, proliferation and apoptosis. Our findings showed a novel molecular mechanism of lung tumorigenesis that may provide new insights for anti-tumor therapies.

Keyphrases

cell cycle
cell proliferation
endothelial cells
oxidative stress
signaling pathway
endoplasmic reticulum stress
cell death
induced pluripotent stem cells
pi k akt