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Here, there and everywhere: T follicular helper cells on the move.

Cindy S MaTri Giang Phan
Published in: Immunology (2017)
T follicular helper (Tfh) cells have the important function of providing B-cell help for the induction of antigen-specific antibody production. As such, it is important to determine the factors that regulate the development, differentiation and function of Tfh cells. This review highlights some of the recent advances in our understanding of Tfh cell migration, Tfh cell memory and the origins and fate of circulating Tfh cells in the blood, that have been revealed from studies in humans and mice.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • cell death
  • signaling pathway
  • oxidative stress
  • stem cells
  • metabolic syndrome
  • mesenchymal stem cells
  • bone marrow
  • working memory
  • case control