Point-Of-Care Tenofovir urine Testing for the Prediction of Treatment Failure and Drug Resistance During Initial Treatment for HIV-1 Infection.
Lucas E HermansChijioke N UmunnakweSamanta T Lalla-EdwardShane K HebelHugo A TempelmanMonique NijhuisWillem D F VenterAnnemarie M J WensingPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Point-of-care objective adherence testing using a urine-TFV test predicted viral rebound with high specificity. In participants with rebound, urine-TFV testing predicted the selection of drug resistance. Objective adherence testing may be used to rapidly provide insight into adherence, suppression, and drug resistance during ART.