Identification of Key Immune Infiltration Related Genes Involved in Aortic Dissection Using Bioinformatic Analyses and Experimental Verification.

Lin Zheng Yusi Yang Jie Liu Tianliang Zhao Xin Zhang Lihua Chen

Published in: Journal of inflammation research (2024)

We identified key immune cells and hub immune cell-related genes involved in AD. Moreover, we found that VWF was co-expressed with the smooth muscle cell marker ACTA2, indicating the important role of VWF in smooth muscle cell loss in AD pathogenesis.

Keyphrases

smooth muscle
aortic dissection
single cell
cell therapy
stem cells
mesenchymal stem cells
network analysis
drug induced
monte carlo